Effect of receiving a customizable brochure on breast cancer patients' knowledge about their diagnosis and treatment: A randomized clinical trial.

BACKGROUND: Patients' lack of knowledge about their own disease may function as a barrier to shared decision-making and well-being. This study aimed to evaluate the impact of written educational materials on breast cancer patients. METHODS: This multicenter, parallel, unblinded, randomized trial included Latin American women aged ≥18 years with a recent breast cancer diagnosis yet to start systemic therapy. Participants underwent randomization in a 1:1 ratio to receive a customizable or standard educational brochure. The primary objective was accurate identification of molecular subtype. Secondary objectives included identification of clinical stage, treatment options, participation in decision-making, perceived quality of information received, and illness uncertainty. Follow-up occurred at 7-21 and 30-51 days post-randomization. CLINICALTRIALS: gov identifier: NCT05798312. RESULTS: One hundred sixty-five breast cancer patients with a median age of 53 years and 61 days from diagnosis were included (customizable: 82; standard: 83). At first available assessment, 52%, 48%, and 30% identified their molecular subtype, disease stage, and guideline-endorsed systemic treatment strategy, respectively. Accurate molecular subtype and stage identification were similar between groups. Per multivariate analysis, customizable brochure recipients were more likely to identify their guideline-recommended treatment modalities (OR: 4.20,p = 0.001). There were no differences between groups in the perceived quality of information received or illness uncertainty. Customizable brochure recipients reported increased participation in decision-making (p = 0.042). CONCLUSIONS: Over one third of recently diagnosed breast cancer patients are incognizant of their disease characteristics and treatment options. This study demonstrates a need to improve patient education and shows that customizable educational materials increase patients' understanding of recommended systemic therapies according to individual breast cancer characteristics.

Intención emprendedora en estudiantes de ciencias de la salud de la Universidad Católica del Uruguay / Intenção empreendedora em estudantes de ciências da saúde da Universidad Católica del Uruguay / Entrepreneurial intention of health sciences' students in the Universidad Católica del Uruguay

Resumen: Esta investigación es un estudio descriptivo que analiza la encuesta realizada a 1.088 estudiantes universitarios por parte del Centro de Desarrollo Emprendedor de la Universidad Católica del Uruguay en el año 2016, en el marco del estudio mundial anual del Global University Entrepreneurial Spirit Students' Survey organizado por la Universidad de St. Gallen-Suiza, auditado por la consultora Ernst & Young. El foco principal es comparar las intenciones emprendedoras de los estudiantes universitarios de la Universidad Católica del Uruguay, en particular los estudiantes de Ciencias de la Salud, versus el resto de los estudiantes. Se plantea la hipótesis de que el nivel de intención de emprender de estudiantes de Ciencias de la Salud es menor respecto al resto de los estudiantes de dicha Universidad, siendo el entorno de la universidad un factor influyente en dicha variable. Tras un análisis cuantitativo de asociaciones estadísticas (pruebas chi-cuadrado) y diferencia de medias significativas, se concluye que dichos estudiantes presentan una menor intención emprendedora que el resto de los estudiantes de la universidad expresada en términos porcentuales, pero las diferencias no son estadísticamente significativas. Sin embargo, sí se constata que el entorno, el clima y las áreas de estudio de la universidad inciden favorablemente en la intención de emprender

Resumo: Esta pesquisa é um estudo descritivo que analisa o levantamento de 1.088 estudantes universitários pelo Centro de Desenvolvimento Empresarial na Universidade Católica do Uruguai em 2016, na pesquisa anual global de Pesquisa Global Universidade Empreendedora Espírito Students' organizado pela a Universidade de St. Gallen-Suíça, auditada pela consultoria Ernst & Young. O foco principal é comparar as intenções empreendedoras dos estudantes universitários da Universidade Católica do Uruguai, em particular os estudantes de Ciências da Saúde, em relação aos demais estudantes. Hipotetiza-se que o nível de intenção de realização de estudantes de Ciências da Saúde seja menor em relação ao restante dos estudantes da referida Universidade, sendo o ambiente da universidade um fator influente na referida variável. Após uma análise quantitativa das associações estatísticas (testes qui-quadrado) e diferença de médias significativas, conclui-se que esses alunos apresentam uma menor intenção empreendedora do que os demais alunos da universidade expressa em termos percentuais, mas as diferenças não são estatisticamente significantes . No entanto, nota-se que o ambiente, clima e áreas de estudo da universidade afetam favoravelmente a intenção de empreender

Abstract: This research is a descriptive study that analyzes the survey conducted on 1088 university students by the Center for Entrepreneurial Development of the Catholic University of Uruguay in 2016, within the framework of the annual global study of the Global University Entrepreneurial Spirit Students' Survey organized by the University of St. Gallen-Switzerland, audited by the consultancy Ernst & Young. The main focus is to compare the entrepreneurial intentions of the university students of the Catholic University of Uruguay, in particular the students of Health Sciences, versus the rest of the students. It is hypothesized that the level of intention to undertake of students of Health Sciences is lower compared to the rest of the students of said University, being the environment of the university an influential factor in said variable. After a quantitative analysis of statistical associations (chi-square tests) and difference of significant means, it is concluded that these students present a lower entrepreneurial intention than the rest of the students of the university expressed in percentage terms, but the differences are not statistically significant . However, it is noted that the environment, climate and study areas of the university favorably affect the intention to undertake